Acetate Fuels the Cancer Engine

نویسندگان

  • Costas A. Lyssiotis
  • Lewis C. Cantley
چکیده

Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and histone modification.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fuels With a High Enthalpy of Evaporation in Si Engine

The increasing use of fuels derived from oil, deepens concern about the fact that non-fossil fuels have to be considered as the fuels of the future. Among the alternatives, hydrogen produced from the abundant sources of water, seems to be one of the best, but it suffers drawbacks with regard to combustion, storage and transportation. The other alternatives are ammonia, produced from unlimited s...

متن کامل

Study of the performance in dual fuels 50% gasoline -50% NG and single original fuels and comparison in part load

One of the most efficient methods to reduce emissions and fuel costs of SI engines in petrol case, is the use of combined gasoline and NG. The ability of an engine is usually expressed with maximum power and maximum torque output of full-load state, but the operating time of the engines with full-load is less than that of part-load time. Therefore, studying the performance of the engine with a ...

متن کامل

Investigation of injection timing and different fuels on the diesel engine performance and emissions

Start of fuel injection and fuel type are two important factors affecting engine performance and exhaust emissions in internal combustion engines. In the present study, a one-dimensional computational fluid dynamics solution with GT-Power software is used to simulate a six-cylinder diesel engine to study the performance and exhaust emissions with different injection timing and alternative fuels...

متن کامل

Hydrogen and Ethanol as Potential Alternative Fuels Compared to Gasoline under Improved Exhaust Gas Recirculation

In the present study, a computational fluid dynamics (CFD) method have been utilized to investigate the effects of exhaust gas recirculation (EGR) and initial charge pressure by means of using a supercharger on the emissions and performance of a SI engine. This engine is fueled separately by gasoline and two potential alternative fuels, hydrogen and ethanol. The results of simulation are compar...

متن کامل

A Comprehensive Comparative Investigation of Compressed Natural Gas as an Alternative Fuel in a Bi-Fuel Spark Ignition Engine

Nowadays, increased attention has been focused on internal combustion engine fuels. Regarding environmental effects of internal combustion engines particularly as sources of pollution and depletion of fossil fuels, compressed natural gas has been introduced as an alternative to gasoline and diesel fuels in many applications. A high research octane number which allows combustion at higher co...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Cell

دوره 159  شماره 

صفحات  -

تاریخ انتشار 2014